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Quantitative Framework

For quantitative research, use the PICO method for developing your research question. This helps in structuring clinical questions and focusing on specific populations and interventions.

The PICO model can help you formulate a good clinical question. Sometimes it's referred to as PICO-T, containing an optional 5th factor. As an example, let's explore a clinical study on diabetes treatment among South Asians. 

P - Patient,  Population, or Problem

What are the most important
characteristics of the patient?

How would you describe a group of
patients similar to yours?

South Asian adults aged 30-60 with diabetes

I - Intervention,  Exposure, Prognostic Factor

What main intervention, prognostic factor, or exposure are you considering?

What do you want to do for the patient
(prescribe a drug, order a test, etc.)?

Introduction of a new
diabetes medication
C - Comparison What is the main alternative to
compare with the intervention?
Current standard
diabetes treatment
O - Outcome What do you hope to accomplish,
measure, improve, or affect?
Improved blood
sugar control
T - Time Factor, Type of Study (optional)

How would you categorize
this question?

What would be the best study
design to answer this question? 

Over 6 months